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Since the introduction of the anti VEGF drug Lucentis by Genentech in 2006, the cost for the treatment for AMD has even further sky rocketed. For example, the cost of these monthly injections to treat all of the new cases of neovascular wet AMD in 2008 in California alone would exceed 9 billion single patient costs per year often is approximately $25k/year. Moreover, studies have shown that the devastating consequences of AMD include the progressive loss of independence and productivity, and increased risks of falls, fractures, and depression among diseased population. So this is not only a problem of the individual quality of life, but also an issue of increasing public health burden and concern. In this study, we will test the feasibility of treating AMD through the transplantation of human embryonic stem cells that have been treated to differentiate into retinal pigment epithelial cells RPE; one of the key cell types known to primarily degenerate or die in AMD. The approach of regenerating the RPE cell layer has many advantages over regenerating photoreceptors and is much more likely to be achieved in the near future. The biggest advantage to RPE cell layer regeneration is that it is preventative and protects or rescues the photoreceptors from degenerating. Also, since it is not a neuronal cell line it does not need to form synapses with the host; a much more difficult task. The success of our preclinical experimentation with RPE replacement therapy will be seamlessly and quickly transferred into clinical trials to develop novel treatments for AMD. Ultimately, hundreds of thousands of Californians with AMD would benefit from our research, with improvement in quality of life and reduced morbidity. The California economy will significantly benefit from this work through potential reduced costs for health care and social welfare.

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Patients being the ones who ultimately shape us the most. The University of Texas Health Science Center at San Antonio, also called UT Health San Antonio, is a leading academic health center with a mission to make lives better through excellence in advanced academics, life saving research and comprehensive clinical care including health, dental and cancer services. Web Privacy | Links from websites affiliated with UT Health's website uthscsa. edu to other websites do not constitute or imply university endorsement of those sites, their content, or products and services associated with those sites. The content on this website is intended to be used for informational purposes only. Health information on this site is not meant to be used to diagnose or treat conditions. Consult a health care provider if you are in need of treatment. Don't know the Reference hours?Need to find the full text of an article?Want to chat with a librarian?Click here for help getting started. Nearly 1 out of 6 people in the world, more than 1 billion people, are migrant workers. Of these migrant workers, 72% are women. The work they do is usually poorly paid, low status work that citizens of wealthier countries are happy to pass on as an "opportunity" to migrants escaping poverty.

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Stroke victims have the best chance if someone around them recognizes the symptoms and acts quickly. Sudden numbness or weakness of the face, arm, or leg especially on one side of the body Sudden confusion, trouble speaking or understanding speech Sudden trouble seeing in one or both eyes Sudden trouble walking, dizziness, loss of balance or coordination Sudden severe headache with no known cause What should a bystander do?If you believe someone is having a stroke if he or she suddenly loses the ability to speak, or move an arm or leg on one side, or experiences facial paralysis on one side call 911 immediately. Stroke is a medical emergency. Every minute counts when someone is having a stroke. The longer blood flow is cut off to the brain, the greater the damage. Immediate treatment can save people's lives and enhance their chances for successful recovery. Why is there a need to act fast?Ischemic strokes, the most common type of strokes, can be treated with a drug called t PA, that dissolves blood clots obstructing blood flow to the brain. The window of opportunity to start treating stroke patients is three hours, but to be evaluated and receive treatment, patients need to get to the hospital within 60 minutes. What is the benefit of treatment?A five year study by the National Institute of Neurological Disorders and Stroke NINDS found that some stroke patients who received t PA within three hours of the start of stroke symptoms were at least 30 percent more likely to recover with little or no disability after three months. What can I do to prevent a stroke?The best treatment for stroke is prevention. There are several risk factors that increase your chances of having a stroke:High blood pressure Heart disease Smoking Diabetes High cholesterol If you smoke quit.

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So for every 8 hours of work effort would equate to 1 FTE, in this example. However, companies where the average employee works 4 days a week or 10 hours a day, the FTE would be 10. The importance is the measurement of the labor work effort to the project. Next, you will want to take the project labor hours estimated and divide that by the hours available during the period of the project. For example, if the estimated labor hours for the project is 4000 hours, but the duration of the project is 6 months or 960 hours, then:This means to reach the project goal based on projected hours, you would need a minimum of 4. 5 FTEs. The half could be resource that would only work on the project part time. The important thing to come out of the calculation is the number of dedicated or Full Time resources needed to reach the project goal. Evaluating internal employee costs can be tricky and is often complicated by various company rules regarding sharing of salary and benefits information with non direct supervisors. This usually results in a battle between project managers and HR in try to determine an accurate accounting of labor that will be associated with a project. However, there are a few things a company can do to make this part of the process easier as well as cut down the interdepartmental stress.